Parker S H, Lovin J D, Jobe W E, Luethke J M, Hopper K D, Yakes W F, Burke B J
Radiology Imaging Associates, Englewood, CO 80011.
Radiology. 1990 Sep;176(3):741-7. doi: 10.1148/radiology.176.3.2167501.
One hundred three patients underwent stereotactic breast biopsy with an 18-, 16-, or 14-gauge cutting needle and a biopsy gun. After biopsy, a localization wire was placed and surgical biopsy performed. There was agreement of the histologic results in 89 cases (87%) including 14 of 16 cancers (87%) (kappa = 0.806). The gun biopsy yielded the correct diagnosis in four cases involving a lesion (including one cancer) that was missed at the surgical biopsy. Nine cases in which the lesion was missed at gun biopsy can be related to insufficient needle size, the greater difficulty in using one of the two stereotactic devices, and early inexperience with the technique. A 14-gauge needle was used in the last 29 biopsies, the results of which agreed with the surgical pathologic findings in 28 cases (97%). With greater experience, stereotactic-guided large-gauge automated percutaneous biopsy may prove to be an acceptable alternative to surgical biopsy in women with breast masses suspected at mammography.
103例患者接受了使用18号、16号或14号切割针及活检枪的立体定向乳腺活检。活检后，放置定位线并进行手术活检。89例（87%）的组织学结果一致，其中16例癌症中有14例（87%）（kappa = 0.806）。活检枪活检在4例手术活检遗漏的病变（包括1例癌症）中得出了正确诊断。9例在活检枪活检时遗漏病变的情况可能与针的尺寸不足、使用两种立体定向设备之一的难度较大以及该技术早期缺乏经验有关。在最后29例活检中使用了14号针，其中28例（97%）的结果与手术病理结果一致。随着经验的增加，对于乳腺钼靶检查怀疑有乳腺肿块的女性，立体定向引导下大口径自动经皮活检可能被证明是手术活检的一种可接受的替代方法。
