Chia K S
Singapore Cancer Registry, Centre for Molecular Epidemiology, c/o Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore.
IARC Sci Publ. 2011(162):183-98.
The Singapore cancer registry is a national registry established in 1968. Cancer registration is done by passive methods. The registry contributed survival data on 45 cancer sites or types registered during 1993-1997. Data on 34 cancers registered during 1968-1997 were utilized for survival trend by period and cohort approaches. Follow-up was done by passive methods, with median follow-up ranging between 2-72 months for different cancers. The proportion with histologically verified diagnosis for various cancers ranged between 27-100%; death certificates only (DCOs) comprised 0-7%; 76-100% of total registered cases were included for the survival analysis. The top-ranking cancers on 5-year age-standardized relative survival rates were nonmelanoma skin (96%), thyroid (90%), testis (88%), corpus uteri (77%), breast (74%), Hodgkin lymphoma (73%) and penis (70%). Five-year relative survival by age group showed either a decreasing trend with increasing age groups or was fluctuating. Localized stage of disease ranged between 18-65% for various cancers and survival decreased with increasing extent of disease. Period survival closely predicted survival experience of cancers diagnosed in that period, and an increasing trend in period survival over different periods indicated an improved prognosis for cancers diagnosed in those calendar periods.
新加坡癌症登记处是一个于1968年设立的国家登记机构。癌症登记通过被动方式进行。该登记处提供了1993 - 1997年期间登记的45种癌症部位或类型的生存数据。利用1968 - 1997年期间登记的34种癌症的数据，采用时期和队列方法分析生存趋势。随访通过被动方式进行，不同癌症的中位随访时间在2 - 72个月之间。各种癌症经组织学确诊的比例在27% - 100%之间；仅依据死亡证明（DCOs）的比例为0% - 7%；生存分析纳入了76% - 100%的登记病例总数。按5年年龄标准化相对生存率排名靠前的癌症有非黑色素瘤皮肤癌（96%）、甲状腺癌（90%）、睾丸癌（88%）、子宫体癌（77%）、乳腺癌（74%）、霍奇金淋巴瘤（73%）和阴茎癌（70%）。按年龄组划分的5年相对生存率显示，要么随年龄组增加呈下降趋势，要么呈波动状态。各种癌症的疾病局限期在18% - 65%之间，且生存率随疾病范围扩大而降低。时期生存率能很好地预测该时期诊断出的癌症患者的生存情况，不同时期时期生存率的上升趋势表明这些日历时期诊断出的癌症患者预后有所改善。
