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[三叉神经痛的现状及其发病机制治疗]

[Status of trigeminal neuralgia and its pathogenetic therapy].

作者信息

Megdiatov R S, Karlov V A, Tebloev I K, Kalashnikov Iu D, Savin A A, Stulin I D, Svetaĭlo L Iu

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(4):13-6.

PMID:2167577
Abstract

As many as 12 patients with the trigeminal algic status, the most severe manifestation of a trigeminal neuralgia exacerbation, were examined. Along with the grave painful syndrome, the patients demonstrated marked vegetovascular disorders, macro- and microcirculatory abnormalities, and hemostatic disorders (the DIC syndrome). For intensive therapy of the condition the authors recommend the use of carbamazepine derivatives, GABA-containing drugs, neuroleptics, antihistamine agents, drugs that improve microcirculation, followed by transcutaneous electric stimulation, allowing the removal of the painful syndrome.

摘要

对多达12例患有三叉神经痛状态(三叉神经痛加重的最严重表现)的患者进行了检查。除了严重的疼痛综合征外,这些患者还表现出明显的植物血管紊乱、大循环和微循环异常以及止血障碍(弥漫性血管内凝血综合征)。为了对该病症进行强化治疗,作者建议使用卡马西平衍生物、含γ-氨基丁酸的药物、抗精神病药、抗组胺药、改善微循环的药物,随后进行经皮电刺激,以消除疼痛综合征。

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