Department of Twin Research and Genetic Epidemiology, King's College, London, UK.
J Sex Med. 2011 Sep;8(9):2420-30. doi: 10.1111/j.1743-6109.2011.02341.x. Epub 2011 Jun 15.
To date, no studies have tried to explore the prevalence and risk factors of recent and lifelong female sexual dysfunction (FSD) in the United Kingdom using validated questionnaires for the assessment of symptom severity and levels of associated sexual distress.
To estimate the prevalence and comorbidity of recent and lifelong FSD and to further identify potential psychosocial and behavioral risk factors in a nationally representative sample of UK women.
One thousand four hundred eighty-nine unselected female twin individuals aged 18-85 years. Validated questionnaires, such as the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale, were used for the assessment of symptom severity and degree of sexual distress.
Prevalence and comorbidity of recent and lifelong FSD according to the FSFI cutoff points and the existence of sexual distress. Lifelong FSD refers to an individual's average sexual function ever since they have been sexually active. We further calculated odds ratios (ORs) with 95% confidence interval for FSD.
We found that 5.8% of women reported any recent sexual dysfunction and 15.5% reported any lifelong sexual dysfunction. Hyposexual desire was the most prevalent recent and lifelong sexual complaint (21.4% and 17.3%, respectively). High intercorrelations were found for both recent and lifelong FSD (r=0.3-0.7). The most common independent, clinical predictor of recent and lifelong FSD diagnosis was relationship dissatisfaction (OR 1.2-4.5). Experience of abuse (OR 1.6-2.1), increased anxiety, and obsessive compulsive behavior were the most common predictors for lifelong FSD.
The study provides the first UK population-based assessment of recent and lifelong FSD using validated outcome measures and accounting for sexual distress. Our results indicate that FSD is common in the general population and is influenced by psychosocial factors with different pathoetiologies underlying recent and lifelong FSD.
迄今为止，尚无研究使用评估症状严重程度和相关性功能障碍严重程度的有效问卷，尝试探索英国女性近期和终身性功能障碍（FSD）的流行率和风险因素。
在英国具有代表性的女性人群中，评估近期和终身 FSD 的流行率和共病率，并进一步确定潜在的心理社会和行为风险因素。
选择 1489 名年龄在 18-85 岁之间的未选择的女性双胞胎个体。使用有效的问卷，如女性性功能指数（FSFI）和女性性功能障碍严重程度指数（FSDS），评估症状严重程度和性困扰程度。
根据 FSFI 临界值和存在性功能障碍，评估近期和终身 FSD 的流行率和共病率。终身 FSD 是指个体自开始有性生活以来的平均性功能。我们进一步计算了 FSD 的优势比（OR）及其 95%置信区间。
我们发现 5.8%的女性报告有任何近期性功能障碍，15.5%报告有任何终身性功能障碍。性欲减退是近期和终身最常见的性功能障碍（分别为 21.4%和 17.3%）。近期和终身 FSD 之间存在高度的相关性（r=0.3-0.7）。近期和终身 FSD 诊断最常见的独立临床预测因素是关系不满意（OR 1.2-4.5）。虐待经历（OR 1.6-2.1）、焦虑增加和强迫行为是终身 FSD 的最常见预测因素。
该研究首次使用有效评估方法和考虑性功能障碍严重程度，对英国人群进行了近期和终身 FSD 的评估。我们的研究结果表明，FSD 在普通人群中很常见，受心理社会因素的影响，近期和终身 FSD 的发病机制不同。
