Kiyozaki H, Teranaka M
Dept. of Surgery, Johana Kousei Hospital.
Gan To Kagaku Ryoho. 1990 Aug;17(8 Pt 1):1513-6.
A 67-year-old woman who received subtotal gastrectomy for advanced gastric cancer in 1985 was diagnosed as having a solitary liver tumor and increasing CA 19-9 for 2 years and 1 month after the operation. When an angiography was performed, we suspected a recurrent liver tumor from gastric cancer, and she received an intra-hepato-arterial infusion of 60 mg of CDDP, 8 mg of MMC and 5 micromilligrams of Lipiodol. The infusion was very effective, so 3 additional infusions were performed. There were no other recurrent lesions, so we performed tumor resection of the liver. Histologically, the resected tissue necrosed and no tumor cell was found. Therefore, it was difficult to diagnose whether the tumor was a recurrent liver tumor or hepatocellular carcinoma. From the clinical diagnosis and X ray findings, we suspected that it was the recurrent liver tumor. We report that this case responded to infusions and all tumor cells which necrosed were rare.
一名67岁女性于1985年因晚期胃癌接受了胃大部切除术，术后2年零1个月被诊断为患有孤立性肝肿瘤且CA 19-9持续升高。进行血管造影时，我们怀疑是胃癌复发的肝肿瘤，她接受了肝动脉内灌注60毫克顺铂、8毫克丝裂霉素和5微克碘油。灌注非常有效，因此又进行了3次灌注。未发现其他复发病变，于是我们对肝脏进行了肿瘤切除。组织学检查显示，切除的组织坏死，未发现肿瘤细胞。因此，很难诊断该肿瘤是复发性肝肿瘤还是肝细胞癌。从临床诊断和X线检查结果来看，我们怀疑是复发性肝肿瘤。我们报告该病例对灌注有反应，且坏死的所有肿瘤细胞都很罕见。
