Une Y, Nagabuchi E, Ogasawara K, Kamiyama T, Sato Y, Kawamukai Y, Sato N, Nakajima Y, Uchino J
First Dept. of Surgery, Hokkaido University School of Medicine.
Gan To Kagaku Ryoho. 1990 Aug;17(8 Pt 2):1643-7.
A case of double cancer, early gastric cancer and hepatocellular carcinoma, was reported. The patient was diabetic and had liver cirrhosis. After gastrectomy for gastric cancer which was hemorrhagic, he was treated by intra-hepatic arterial infusion chemotherapy followed by hepatic resection. Histopathologically, about half of the main tumor showed necrosis, but very viable new cancer cell nests were seen around the main nodule. The patient is in good condition without recurrence of hepatic lesion 1 year after resection. The usefulness of arterial infusion chemotherapy was demonstrated in the case of double cancer, in which it is difficult to resect both cancers simultaneously.
报告了一例同时患有早期胃癌和肝细胞癌的双原发癌病例。该患者患有糖尿病和肝硬化。在对出血性胃癌进行胃切除术后，对其进行了肝动脉内灌注化疗，随后进行了肝切除。组织病理学检查显示，约一半的主要肿瘤出现坏死，但在主要结节周围可见非常活跃的新癌细胞巢。切除术后1年，患者状况良好，肝脏病变未复发。对于双原发癌病例，在难以同时切除两种癌症的情况下，动脉灌注化疗的有效性得到了证实。
