鼻出血儿童鼻中隔可见血管的病理学
The pathology of visible blood vessels on the nasal septum in children with epistaxis.
作者信息
Montague Mary-Louise, Whymark Andrew, Howatson Allan, Kubba Haytham
机构信息
Department of Paediatric Otolaryngology, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, Scotland, United Kingdom.
出版信息
Int J Pediatr Otorhinolaryngol. 2011 Aug;75(8):1032-4. doi: 10.1016/j.ijporl.2011.05.011. Epub 2011 Jun 15.
OBJECTIVE
Epistaxis is common in children, but its cause remains unknown. About half the children who present with epistaxis have prominent vessels on the nasal septum. The aim of this study was to determine the pathological nature of the prominent septal vessels in children with recurrent epistaxis.
METHODS
4mm punch biopsies of the nasal septal mucosa were taken from 5 children undergoing nasal cautery under general anaesthesia.
RESULTS
Histology showed that the prominent vessels were thin-walled arterioles and capillaries with a surrounding inflammatory infiltrate. There was no evidence of venous varicosities or arterial microaneurysms.
CONCLUSION
We postulate a mechanism for septal neovascularisation due to chronic low-grade inflammation as a cause for recurrent epistaxis in children.
目的
鼻出血在儿童中很常见，但其病因尚不清楚。约一半出现鼻出血的儿童鼻中隔上有明显的血管。本研究的目的是确定复发性鼻出血儿童鼻中隔明显血管的病理性质。
方法
从5例在全身麻醉下接受鼻腔烧灼术的儿童中取4毫米鼻中隔黏膜活检组织。
结果
组织学显示，明显的血管是薄壁小动脉和毛细血管，周围有炎性浸润。没有静脉曲张或动脉微动脉瘤的证据。
结论
我们推测慢性低度炎症导致鼻中隔新生血管形成的机制是儿童复发性鼻出血的原因。
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