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Invasive Klebsiella pneumoniae infections, California, USA.美国加利福尼亚州侵袭性肺炎克雷伯菌感染
Emerg Infect Dis. 2010 Sep;16(9):1490-1. doi: 10.3201/eid1609.100386.
2
Clinical and bacteriological characteristics of pyogenic liver abscess in non-diabetic patients.非糖尿病患者化脓性肝脓肿的临床和细菌学特征。
J Microbiol Immunol Infect. 2009 Oct;42(5):385-92.
3
Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization.肺炎克雷伯菌的毒力克隆：基于基因组和表型特征的鉴定及进化情况
PLoS One. 2009;4(3):e4982. doi: 10.1371/journal.pone.0004982. Epub 2009 Mar 25.
4
Invasive infection with hypermucoviscous Klebsiella pneumoniae: multiple cases presenting to a single emergency department in the United States.高黏液性肺炎克雷伯菌侵袭性感染：美国一家急诊科收治的多例病例
Ann Emerg Med. 2009 May;53(5):639-42. doi: 10.1016/j.annemergmed.2008.11.007. Epub 2009 Jan 8.
5
Evaluation of a multiplex PCR for detection of serotypes K1, K2 and K5 in Klebsiella sp. and comparison of isolates within these serotypes.用于检测克雷伯菌属中K1、K2和K5血清型的多重聚合酶链反应评估以及这些血清型内分离株的比较
FEMS Microbiol Lett. 2008 Jul;284(2):247-52. doi: 10.1111/j.1574-6968.2008.01208.x. Epub 2008 May 27.
6
Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections.克雷伯菌的毒力特征及肺炎克雷伯菌血流感染的临床表现。
Emerg Infect Dis. 2007 Jul;13(7):986-93. doi: 10.3201/eid1307.070187.
7
Genetically similar isolates of Klebsiella pneumoniae serotype K1 causing liver abscesses in three continents.在三大洲引发肝脓肿的肺炎克雷伯菌血清型K1的基因相似分离株。
J Med Microbiol. 2007 May;56(Pt 5):593-597. doi: 10.1099/jmm.0.46964-0.
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Polymerase chain reaction analysis for detecting capsule serotypes K1 and K2 of Klebsiella pneumoniae causing abscesses of the liver and other sites.用于检测引起肝脓肿及其他部位脓肿的肺炎克雷伯菌荚膜血清型K1和K2的聚合酶链反应分析。
J Infect Dis. 2007 Apr 15;195(8):1235-6; author reply 1236. doi: 10.1086/512686.
9
Capsular serotype K1 or K2, rather than magA and rmpA, is a major virulence determinant for Klebsiella pneumoniae liver abscess in Singapore and Taiwan.在新加坡和台湾地区，荚膜血清型K1或K2而非magA和rmpA是肺炎克雷伯菌肝脓肿的主要毒力决定因素。
J Clin Microbiol. 2007 Feb;45(2):466-71. doi: 10.1128/JCM.01150-06. Epub 2006 Dec 6.
10
Clinical implications of hypermucoviscosity phenotype in Klebsiella pneumoniae isolates: association with invasive syndrome in patients with community-acquired bacteraemia.肺炎克雷伯菌分离株高黏液性表型的临床意义：与社区获得性菌血症患者侵袭性综合征的关联
J Intern Med. 2006 Jun;259(6):606-14. doi: 10.1111/j.1365-2796.2006.01641.x.

法国两所大学医院出现严重且致命的肺炎克雷伯菌感染。

Emerging severe and fatal infections due to Klebsiella pneumoniae in two university hospitals in France.

机构信息

Laboratoire de Bactériologie, Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France.

出版信息

J Clin Microbiol. 2011 Aug;49(8):3012-4. doi: 10.1128/JCM.00676-11. Epub 2011 Jun 15.

DOI:10.1128/JCM.00676-11
PMID:21677064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3147753/
Abstract

Severe infections caused by hypermucoviscous Klebsiella pneumoniae have been reported in Southeast Asian countries over the past several decades. This report shows their emergence in France, with 12 cases observed during a 2-year period in two university hospitals. Two clones (sequence type 86 [ST86] and ST380) of serotype K2 caused five rapidly fatal bacteremia cases, three of which were associated with pneumonia, whereas seven liver abscess cases were caused by K1 strains of ST23.

摘要

在过去几十年中，东南亚国家报告了由高黏液性肺炎克雷伯菌引起的严重感染。本报告显示其在法国的出现，在两所大学医院的 2 年期间观察到 12 例病例。两个克隆（血清型 86 [ST86]和 ST380）引起了 5 例迅速致命的菌血症病例，其中 3 例与肺炎有关，而 7 例肝脓肿病例由 ST23 的 K1 株引起。