奥沙西泮诱导的睡眠驾驶和与睡眠相关的摄食障碍。
Sodium oxybate-induced sleep driving and sleep-related eating disorder.
机构信息
Department of Neurology, Sleep Medicine Division, University of Miami Miller School of Medicine, Miami, FL, USA.
出版信息
J Clin Sleep Med. 2011 Jun 15;7(3):310-1. doi: 10.5664/JCSM.1082.
Abstract
Hypnosedative-induced complex behaviors have gained increased attention in recent years as a potential complication of benzodiazepines and benzodiazepine-receptor agonist use. Sodium oxybate (SO), the sodium salt of γ-hydroxybutyrate, an inhibitory neurotransmitter, has been associated with dose-dependent rates of somnambulism; however, there is limited information about complex motor behaviors with SO. We describe a patient with narcolepsy-cataplexy who experienced one episode of sleep-driving and at least two sleep-related eating episodes with therapeutic doses of SO.
摘要
近年来，作为苯二氮䓬类药物和苯二氮䓬受体激动剂使用的潜在并发症，催眠诱导的复杂行为受到了越来越多的关注。γ-羟基丁酸（GHB）的钠盐——羟丁酸钠（SO）是一种抑制性神经递质，与剂量相关的梦游发生率有关；然而，关于 SO 引起的复杂运动行为的信息有限。我们描述了一例伴有发作性睡病猝倒的患者，在接受 SO 的治疗剂量时，经历了一次睡眠驾驶和至少两次与睡眠相关的进食发作。
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