Stride P
Redcliffe Hospital, Redcliffe, Queensland, Australia.
J R Coll Physicians Edinb. 2011 Jun;41(2):169-73. doi: 10.4997/JRCPE.2011.210.
Egill Skallagrímsson, a tenth-century Viking, was a colourful warrior poet and an early anti-hero. The thickness and strength of his skull and his very ugly facial features with a prominent mandible have suggested to some authorities that Egill suffered from Paget's disease of bone. However, Paget's bone, while thickened, lacks structural integrity, infrequently involves the mandible and is prone to fractures. The more recent discoveries of sclerosing bone diseases, the elucidation of their pathophysiological abnormalities in intracellular signalling in bones and current research on the sclerostin or LRP5 genes suggest Van Buchem disease as a more probable diagnosis, although the hypothesis remains conjecture in the absence of any of his remains.
埃吉尔·斯卡拉格里姆松是一位10世纪的维京人，他是一位富有传奇色彩的 warrior poet 和早期的反英雄人物。他颅骨的厚度和强度以及他那有着突出下颌骨的极其丑陋的面部特征，让一些权威人士认为埃吉尔患有佩吉特骨病。然而，佩吉特骨虽然增厚，但缺乏结构完整性，很少累及下颌骨，且容易骨折。最近对硬化性骨病的发现、对其骨细胞内信号传导病理生理异常的阐明以及对硬化蛋白或LRP5基因的当前研究表明，范布赫姆病是一个更有可能的诊断，尽管在没有他任何遗骸的情况下，这一假设仍只是推测。 （注：“warrior poet”直译为“ warrior poet”，可能是特定语境下的某种称呼，这里保留英文未翻译，可根据实际情况补充准确译法）
