Man Yu Bon, Chow Ka Lai, Wang Hong Sheng, Lau Ka Yan, Sun Xiao Lin, Wu Sheng Chun, Cheung Kwai Chung, Chung Shan Shan, Wong Ming Hung
Croucher Institute for Environmental Sciences, and Department of Biology, Hong Kong Baptist University, Hong Kong, PR China.
J Environ Monit. 2011 Aug;13(8):2250-9. doi: 10.1039/c1em10168d. Epub 2011 Jun 16.
The aim of this study was to evaluate the consequence of changing land use from agriculture land to other use purposes with respect to OCPs non-cancer and cancer risk on human health, based on concentrations of DDTs and HCHs in soils collected from 55 locations representing 12 different land use types. There were no non-cancer risks of DDTs and γ-HCHs on adults and children, and there were very low cancer risks of DDD, o,p'-DDE, DDT, α-HCH, β-HCH, γ-HCH based on their total concentrations in all samples. Nonetheless, there were significant correlations of DDT to its metabolites (DDE and DDD) (r = 0.506 and r = 0.648) and DDE to DDD (r = 0.438) both at p < 0.01. OCP levels should be routinely monitored in different environmental media and food in order to verify whether there is fresh input. Their potential risks on human health should also be assessed.
本研究的目的是基于从代表12种不同土地利用类型的55个地点采集的土壤中滴滴涕（DDTs）和六六六（HCHs）的浓度，评估农业用地转变为其他用途对人类健康造成的有机氯农药非致癌和致癌风险的影响。滴滴涕和γ-六六六对成人和儿童不存在非致癌风险，基于所有样本中滴滴滴（DDD）、邻对滴滴伊（o,p'-DDE）、滴滴涕、α-六六六、β-六六六、γ-六六六的总浓度，其致癌风险非常低。尽管如此，滴滴涕与其代谢物（滴滴伊和滴滴滴）之间存在显著相关性（r = 0.506和r = 0.648），滴滴伊与滴滴滴之间也存在显著相关性（r = 0.438），两者的p值均<0.01。应定期监测不同环境介质和食品中的有机氯农药水平，以核实是否有新的输入。还应评估它们对人类健康的潜在风险。
