Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, 161 Cathedral Street, Glasgow G40RE, UK.
J Pharm Biomed Anal. 2011 Sep 10;56(2):246-55. doi: 10.1016/j.jpba.2011.05.022. Epub 2011 May 23.
The recent global increase in the abuse of 4'-methylmethcathinone and related compounds has developed a requirement for full chemical characterisation of these products. In this work we present full synthetic and chemical characterisation data and supplemental information for mephedrone synthesised as both the hydrobromide and hydrochloride salt. Additionally we report the first fully validated chromatographic methods for the detection and quantitative analysis of the substance both in its pure form and in the presence of a number of common adulterants used in illicit drug manufacture.
最近全球范围内对 4'-甲基甲卡西酮和相关化合物的滥用有所增加，这就需要对这些产品进行全面的化学特性分析。在这项工作中，我们提供了甲卡西酮的全合成和化学特性分析数据以及补充信息，包括氢溴酸盐和盐酸盐两种盐形式。此外，我们还报告了首个经过全面验证的色谱检测方法，可用于对该物质进行纯物质和常见非法药物制造中使用的多种掺杂物的定量分析。
