Sachdeva Reecha, Schoenfield Lynn, Marcotty Andreas, Singh Arun D
Cleveland Clinic, Cole Eye Institute, Cleveland, Ohio 44124, USA.
J AAPOS. 2011 Jun;15(3):302-4. doi: 10.1016/j.jaapos.2011.02.013. Epub 2011 Jun 15.
We describe a case of unilateral retinoblastoma in a 13-month-old boy who presented with signs of orbital cellulitis. Heterochromia, hyphema, and vitreous hemorrhage were observed. Initial computed tomography (CT) imaging failed to reveal the calcified intraocular mass that was later identified on ultrasonography. Histopathology of the enucleated eye revealed diffuse inflammation and tumor necrosis but with absence of malignant retinoblastoma cells. Genetic testing was equivocal. The patient is presumed to have had retinoblastoma that underwent autoinfarction, leading to secondary inflammation. This case highlights the importance of complete ocular evaluation and proper imaging modalities in children presenting with orbital cellulitis.
我们描述了一例13个月大患有单侧视网膜母细胞瘤的男孩，其表现出眼眶蜂窝织炎的症状。观察到有虹膜异色、前房积血和玻璃体出血。最初的计算机断层扫描（CT）成像未能显示出钙化的眼内肿块，该肿块后来在超声检查中被发现。摘除眼球的组织病理学检查显示有弥漫性炎症和肿瘤坏死，但未发现恶性视网膜母细胞瘤细胞。基因检测结果不明确。推测该患者曾患视网膜母细胞瘤，肿瘤发生了自身梗死，进而导致继发性炎症。该病例凸显了对患有眼眶蜂窝织炎的儿童进行全面眼部评估和采用适当成像方式的重要性。
