Department of Obstetrics & Gynecology, Korea University College of Medicine, Seoul, Korea.
Scott Med J. 2011 May;56(2):120. doi: 10.1258/smj.2011.011100.
Primary hepatoid adenocarcinoma of the endometrium is a rare tumour that is similar to hepatocellular carcinoma histologically. Here, a patient with primary hepatoid carcinoma of the endometrium with a high alphafetoprotein (AFP) level (90,508 ng/mL) is presented in a 75-year-old woman. The pelvic computed tomography and magnetic resonance imaging suggested a submucosal leiomyoma with degeneration or endometrial hyperplasia. However, the endometrial biopsy revealed a primary hepatoid carcinoma of the endometrium. The patient underwent a staging laparotomy including a total abdominal hysterectomy, bilateral salpingo-oophorectomy and lymph node sampling with pelvic cytology. The AFP level can be highly elevated in hepatoid carcinoma of the endometrium.
子宫内膜原发肝样腺癌是一种罕见的肿瘤，在组织学上类似于肝细胞癌。本文报道了一例 75 岁女性子宫内膜原发肝样腺癌患者，其甲胎蛋白（AFP）水平较高（90,508ng/ml）。盆腔 CT 和 MRI 提示黏膜下肌瘤变性或子宫内膜增生。然而，子宫内膜活检显示为子宫内膜原发肝样腺癌。患者接受了分期手术，包括全子宫切除术、双侧附件切除术和淋巴结取样及盆腔细胞学检查。在子宫内膜原发肝样腺癌中，AFP 水平可能会显著升高。
