Kramer J, Schratter M, Pongracz N, Neuhold A, Stiglbauer R, Imhof H
Universitätsklinik für Radiodiagnostik, Universität Wien.
Rofo. 1990 Aug;153(2):131-6. doi: 10.1055/s-2008-1033350.
MRI of proven spondylitis was performed in 39 patients. Acute spondylitis appeared hypointense on T1-weighted and hyperintense on T2-weighted images. Following intravenous application of Gd-DTPA, enhancement of the marrow and disk was seen. With progressive healing increasing signal was seen on T1-weighted images. This was caused by the presence of focal fat marrow representing the first sign of therapy response. Corresponding to the clinical healing process T1-signal increased due to fatty marrow, while the T2-signal decreased as well as the enhancement following Gd-DTPA application. Therefore, MR imaging can be recommended as the method of choice for early diagnosis of spondylitis and assessment of therapy response.