Kohda M, Manabe T, Ueki H
Department of Dermatology, Kawasaki Medical School, Kurashiki, Japan.
Am J Dermatopathol. 1990 Aug;12(4):344-9. doi: 10.1097/00000372-199008000-00003.
The presence of squamous cells in eccrine neoplasms is not well recognized, but is usually considered to denote malignant transformation. The small nests composed of squamoid cells (squamous islands), however, were found in 46% of the eccrine neoplasms we studied. They were divided into three types according to their location, histological structure, and degree of cellular atypia. These types possibly represented intermingling of epidermis or hair follicle, squamous syringo-metaplasia, and malignant transformation. We would like to stress that squamous islands are seen not only in malignant eccrine neoplasms, but also in benign ones, and that their presence should not be interpreted as evidence of malignancy.
小汗腺肿瘤中鳞状细胞的存在尚未得到充分认识，但通常被认为表示恶性转化。然而，在我们研究的46%的小汗腺肿瘤中发现了由鳞状样细胞组成的小巢（鳞状岛）。根据其位置、组织结构和细胞异型程度，这些类型被分为三种。这些类型可能代表了表皮或毛囊的混合、鳞状汗腺化生以及恶性转化。我们想强调的是，鳞状岛不仅见于恶性小汗腺肿瘤，也见于良性肿瘤，其存在不应被解释为恶性的证据。
