Clark Shane, Young Adam, Piatigorsky Eli, Ravitskiy Larisa
Department of Internal Medicine, Division of Dermatology, The Ohio State University Medical Center, Columbus, Ohio.
J Clin Aesthet Dermatol. 2013 Apr;6(4):33-6.
The purpose of this case report and literature review was to summarize the current knowledge surrounding this rare cutaneous tumor and promote awareness of the success of Mohs micrographic surgery as a definitive therapeutic modality in a case of squamoid eccrine ductal carcinoma.
Case report and literature review.
Squamoid eccrine ductal carcinoma has been introduced as a rare type of eccrine carcinoma with only eight previously reported cases in the literature. Despite the tumor's introduction as a type of eccrine carcinoma, the true etiology is currently contentious; the lesion represents a diagnostic challenge, and its malignant potential remains uncertain. Thus, proper histological diagnosis and definitive management are under active discussion.
Index case patient records review and peer-reviewed literature.
The authors present the ninth reported case of squamoid eccrine ductal carcinoma and the third report of Mohs micrographic surgery for complete extirpation of the lesion.
The anecdotal success of Mohs micrographic surgery as a therapeutic modality in the treatment of three cases of squamoid eccrine ductal carcinoma (including the case reported herein) suggests that this is an effective yet tissue-sparing surgical modality. However, given the poorly understood natural history of squamoid eccrine ductal carcinoma and the uncertainty of the lesion's etiological and malignant taxonomy, further experiences with this tumor are necessary and close follow up of patients is suggested.
本病例报告及文献综述的目的是总结关于这种罕见皮肤肿瘤的现有知识，并提高对莫氏显微外科手术作为鳞状小汗腺导管癌一种确定性治疗方式取得成功的认识。
病例报告及文献综述。
鳞状小汗腺导管癌已被引入作为一种罕见的小汗腺癌类型，文献中此前仅报道过8例。尽管该肿瘤被引入作为小汗腺癌的一种类型，但其真正病因目前仍存在争议；该病变代表了一项诊断挑战，其恶性潜能仍不确定。因此，恰当的组织学诊断和确定性治疗正在积极讨论中。
索引病例患者记录回顾及同行评议文献。
作者呈现了第9例报道的鳞状小汗腺导管癌病例以及第3例关于莫氏显微外科手术完整切除该病变的报告。
莫氏显微外科手术作为一种治疗方式在3例鳞状小汗腺导管癌（包括本文报道的病例）治疗中取得的成功经验表明，这是一种有效且能保留组织的手术方式。然而，鉴于对鳞状小汗腺导管癌自然史了解不足以及该病变病因和恶性分类的不确定性，有必要积累更多关于这种肿瘤的经验，并建议对患者进行密切随访。
