五年的 siRNA 递呈：聚焦金纳米粒子。

Five years of siRNA delivery: spotlight on gold nanoparticles.

机构信息

Massachusetts Institute of Technology, Cambridge, MA, USA.

出版信息

Small. 2011 Jul 18;7(14):1932-7. doi: 10.1002/smll.201100761. Epub 2011 Jun 17.

DOI:10.1002/smll.201100761

PMID:21681985

Abstract

Gold nanoparticles have become widely used in scientific research due to their unique physical and chemical properties. In the last several years their use as siRNA delivery agents has been investigated. Here, progress made using gold nanoparticles for siRNA delivery is described and the different strategies employed are compared.

摘要

金纳米颗粒由于其独特的物理和化学性质，已在科学研究中得到广泛应用。在过去几年中，人们研究了将其用作 siRNA 递药载体。本文介绍了使用金纳米颗粒进行 siRNA 递药的进展，并比较了所采用的不同策略。