非诺贝特：肾功能改变。
Fenofibrate: altered renal function.
出版信息
Prescrire Int. 2011 Jun;20(117):154-5.
PMID:21682015
Abstract
In patients with type 2 diabetes, a subgroup analysis of a placebo-controlled trial of fenofibrate showed a significant decline in calculated creatinine clearance with fenofibrate. Most fibrates seem to have a detrimental effect on renal function, with the probable exception of gemfibrozil, which is the fibrate of choice in the few situations in which a fibrate is needed.
摘要
在2型糖尿病患者中，一项非诺贝特安慰剂对照试验的亚组分析显示，使用非诺贝特后计算的肌酐清除率显著下降。大多数贝特类药物似乎对肾功能有不利影响，吉非贝齐可能是个例外，在少数需要使用贝特类药物的情况下，它是首选的贝特类药物。
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