Westheimer Gerald
Division of Neurobiology, University of California, Berkeley, CA 94720, USA.
Clin Exp Optom. 2012 Jan;95(1):109-12. doi: 10.1111/j.1444-0938.2011.00627.x. Epub 2011 Jun 20.
Changes in cortical receptive fields following deafferentation raise the question of whether interruption of optic nerve fibres engenders spatial distortion in the region bordering the resulting scotoma.
The regularity and uniformity of the spatial metric surrounding a monocular Bjerrum scotoma were studied in both the affected and unaffected eyes of a glaucoma patient, using rigorous psychometric measurements and Amsler grid observations.
No expansion of distances towards the edge of the scotoma was found; however, such a change occurs at the border of the normal blind spot, though not binocularly and not in the corresponding field of the other eye.
The findings argue against cortical reorganisation following monocular retinal deafferentation in the adult.
去传入后皮质感受野的变化引发了一个问题，即视神经纤维的中断是否会在由此产生的暗点边界区域导致空间扭曲。
使用严格的心理测量方法和阿姆斯勒方格表观察，研究了一名青光眼患者患眼和未患眼单眼 Bjerrum 暗点周围空间度量的规律性和均匀性。
未发现朝向暗点边缘的距离有扩大；然而，这种变化发生在正常盲点的边界，尽管不是双眼同时出现，也不在另一只眼的相应视野中。
这些发现反对成人单眼视网膜去传入后的皮质重组。
