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来自巨桉的三种新型爱泼斯坦-巴尔病毒激活抑制剂euglobal-G1、-G2和-G3的结构

Structures of euglobal-G1, -G2, and -G3 from Eucalyptus grandis, three new inhibitors of Epstein-Barr virus activation.

作者信息

Takasaki M, Konoshima T, Shingu T, Tokuda H, Nishino H, Iwashima A, Kozuka M

机构信息

Kyoto Pharmaceutical University, Japan.

出版信息

Chem Pharm Bull (Tokyo). 1990 May;38(5):1444-6. doi: 10.1248/cpb.38.1444.

DOI:10.1248/cpb.38.1444
PMID:2168298
Abstract

Three new euglobals with acylphloroglucinol-monoterpene structures, named euglobal -G1 (1), -G2 (2), and -G3 (3) were isolated from the chloroform extract of the juvenile leaves of Eucalyptus grandis (Myrtaceae). The structures of these new compounds were determined on the basis of their spectral data. The compounds strongly inhibited the Epstein-Barr virus activation.

摘要

从巨桉(桃金娘科)幼叶的氯仿提取物中分离出三种具有酰基间苯三酚-单萜结构的新优球蛋白,命名为优球蛋白-G1(1)、-G2(2)和-G3(3)。这些新化合物的结构根据其光谱数据确定。这些化合物强烈抑制爱泼斯坦-巴尔病毒的激活。

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