Department of Obstetrics and Gynecology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
Int J Gynaecol Obstet. 2011 Aug;114(2):124-7. doi: 10.1016/j.ijgo.2011.04.002. Epub 2011 Jun 16.
To evaluate follicle loss in ovarian tissue after laparoscopic excision by the stripping technique in endometriomas versus benign nonendometriotic ovarian cysts.
Cystectomy samples obtained from 127 ovaries from 104 patients (mean age, 29.05 ± 05 years; range, 19-40 years) by laparoscopic excision (61 endometriomas and 66 benign nonendometriotic cysts) were evaluated for follicle loss. The samples including normal ovarian tissue were graded on a semiquantitative scale from 0 to 4, where 0 was complete absence of follicles and 4 was the pattern of primary and secondary follicles seen in a normal ovary. The results from endometriomas were compared with those from nonendometriotic cysts.
There were no differences in mean tissue thickness, or number of primordial, primary, or secondary follicles between the endometriomas and the nonendometriotic cysts (P > 0.05). Ovarian cortex was detected in 92% and 82% of the endometriomas and nonendometriotic samples, respectively, (P = 0.081). Semiquantitative scoring of ovarian tissue was significantly higher in endometriomas (1.64 ± 1.35 versus 1.11 ± 1.22, P = 0.022).
In up to 92% of the cystectomy samples, normal ovarian tissue was found adjacent to the benign cyst; however, functional follicle loss was slightly, but significantly, higher in the endometriomas.
评估卵巢子宫内膜异位囊肿和良性非子宫内膜异位性卵巢囊肿经腹腔镜剔除术后卵泡丢失情况。
对 104 例（年龄 29.05±05 岁，范围 19-40 岁）患者的 127 个卵巢囊肿（61 个卵巢子宫内膜异位囊肿和 66 个良性非子宫内膜异位性卵巢囊肿）进行腹腔镜剔除术时获取的囊肿切除术标本进行评估，以评估卵泡丢失情况。对包括正常卵巢组织的标本进行半定量评分，范围为 0 至 4 分，其中 0 分为完全无卵泡，4 分为正常卵巢中可见初级和次级卵泡的模式。将子宫内膜异位囊肿的结果与非子宫内膜异位性囊肿的结果进行比较。
子宫内膜异位囊肿和非子宫内膜异位性囊肿之间的平均组织厚度、原始卵泡、初级卵泡或次级卵泡数量均无差异（P＞0.05）。卵巢皮质在子宫内膜异位囊肿和非子宫内膜异位性囊肿中的检出率分别为 92%和 82%（P=0.081）。子宫内膜异位囊肿的卵巢组织半定量评分明显更高（1.64±1.35 比 1.11±1.22，P=0.022）。
在多达 92%的囊肿切除术标本中，良性囊肿旁发现了正常卵巢组织；然而，子宫内膜异位囊肿中功能性卵泡丢失略高，但有统计学意义。
