NASA Langley Research Center, Hampton, VA 23681 USA.
Ultrasound Med Biol. 2011 Aug;37(8):1340-9. doi: 10.1016/j.ultrasmedbio.2011.05.009. Epub 2011 Jun 17.
We have modeled the removal of emboli from cardiopulmonary bypass circuits via acoustic radiation force. Unless removed, emboli can result in cognitive deficit for those undergoing heart surgery with the use of extracorporeal circuits. There are a variety of mathematical formulations in the literature describing acoustic radiation force, but a lingering question that remains is how important viscosity of the blood and/or embolus is to the process. We implemented both inviscid and viscous models for acoustic radiation force on a sphere immersed in a fluid. We found that for this specific application, the inviscid model seems to be sufficient for predicting acoustic force upon emboli when compared with the chosen viscous model. Thus, the much simpler inviscid model could be used to optimize experimental techniques for ultrasonic emboli removal.
我们已经通过声辐射力对体外循环回路中的栓子去除进行了建模。如果不清除栓子，体外循环心脏手术患者可能会出现认知功能障碍。文献中有多种数学公式可用于描述声辐射力，但仍存在一个悬而未决的问题，即血液和/或栓子的粘性对该过程的重要性。我们在浸入流体中的球体上实现了无粘和粘性声辐射力模型。我们发现，对于这种特定的应用，与所选择的粘性模型相比，无粘模型似乎足以预测栓子上的声力。因此，更简单的无粘模型可用于优化超声栓子去除的实验技术。
