男性乳腺色素沉着性佩吉特病

Pigmented Paget's disease of the male breast.

作者信息

Ho T C, St Jacques M, Schopflocher P

机构信息

Department of Medicine, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada.

出版信息

J Am Acad Dermatol. 1990 Aug;23(2 Pt 2):338-41. doi: 10.1016/0190-9622(90)70217-6.

DOI:10.1016/0190-9622(90)70217-6

PMID:2168446

Abstract

Paget's disease of the breast presents as an eczematous lesion of the nipple. Histologically, it is characterized by malignant intraepidermal cells associated with an underlying ductal carcinoma. Paget's disease of the male breast is rare. Although melanin has been found within the malignant cells of Paget's disease, no clinically pigmented lesion has yet been reported. We present a case of pigmented Paget's disease of the male breast and review the pathogenesis of this disease.

摘要

乳腺佩吉特病表现为乳头的湿疹样病变。组织学上，其特征为恶性表皮内细胞伴发潜在的导管癌。男性乳腺佩吉特病罕见。尽管在佩吉特病的恶性细胞内已发现黑色素，但尚未有临床色素沉着病变的报道。我们报告一例男性乳腺色素沉着性佩吉特病病例，并对该疾病的发病机制进行综述。