Moghimi-Dehkordi Bijan, Vahedi Mohsen, Khoshkrood Mansoori Babak, Kasaeian Amir, Safaee Azadeh, Habibi Manijeh, Pourhoseingholi Asma, Pourhoseingholi Mohammad Amin, Zali Mohammad Reza
Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Science, Taleghani Hospital, Tabnak Street/Yaman Avenue, Velenjak, Tehran, Iran.
Arab J Gastroenterol. 2011 Jun;12(2):86-9. doi: 10.1016/j.ajg.2011.03.005. Epub 2011 May 6.
Gastro-oesophageal reflux disease (GERD) and dyspepsia are common digestive disorders that inflict serious harm, burden and economic consequences on individuals worldwide. The aim of this study was to estimate the direct and indirect economic burden of GERD and dyspepsia in the whole population of Tehran, the capital of Iran.
The study was performed on a total of 18,180 adult subjects (age>18 years) taken as a random sample in Tehran province, Iran (2006-2007). A valid and reliable questionnaire was used to enquire about the symptoms of GERD, dyspepsia and the frequency of the utilization of health services including physician visits, hospitalisations and productivity loss due to GERD/dyspepsia symptoms in the preceding 6 months.
GERD was found in 518 (41.9% males) patients and dyspepsia in 404 patients (38.9% males). Further 1007 subjects had both GERD and dyspepsia. The total direct costs of disease per patient for GERD, dyspepsia and their overlap were PPP$97.70, PPP$108.10 and PPP$101.30, respectively (PPP, purchasing power parity dollars). The total indirect cost of disease per patient was PPP$13.7, PPP$12.1 and PPP$32.7, for GERD, dyspepsia and their overlap, respectively.
According to our results, hospitalisation and physician visits were the main cost of disease that could be minimised by revision of the insurance business in Iran.
胃食管反流病（GERD）和消化不良是常见的消化系统疾病，给全球个人带来严重危害、负担和经济后果。本研究旨在评估伊朗首都德黑兰全体居民中GERD和消化不良的直接和间接经济负担。
本研究对伊朗德黑兰省（2006 - 2007年）随机抽取的18180名成年受试者（年龄>18岁）进行。使用有效且可靠的问卷询问GERD、消化不良症状以及过去6个月内包括看医生、住院和因GERD/消化不良症状导致的生产力损失等医疗服务利用频率。
发现518例患者患有GERD（男性占41.9%），404例患者患有消化不良（男性占38.9%）。另有1007名受试者同时患有GERD和消化不良。GERD、消化不良及其重叠情况的每位患者疾病直接总成本分别为97.70购买力平价美元、108.10购买力平价美元和101.30购买力平价美元（PPP，购买力平价美元）。GERD、消化不良及其重叠情况的每位患者疾病间接总成本分别为13.7购买力平价美元、12.1购买力平价美元和32.7购买力平价美元。
根据我们的研究结果，住院和看医生是主要的疾病成本，可通过修订伊朗的保险业务来尽量降低。
