Birmingham/Atlanta Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, University of Alabama at Birmingham, Birmingham, Alabama 35249-7333, USA.
J Urol. 2011 Aug;186(2):589-93. doi: 10.1016/j.juro.2011.03.114.
We estimate trends in the prevalence of urinary incontinence in the adult population of the United States from 2001 through 2008 before and after adjusting for other potential associated factors.
We analyzed data on 17,850 adults 20 years old or older who participated in the 2001 to 2008 cycles of the National Health and Nutrition Examination Survey. Any urinary incontinence was defined as a positive response to questions on urine leakage during physical activity, before reaching the toilet and during nonphysical activity. During this period changes in demographic and clinical factors associated with urinary incontinence included age, race/ethnicity, obesity, diabetes and chronic medical conditions (prostate disease in men). Age standardized prevalence estimates and prevalence ORs of urinary incontinence trends were determined using adjusted multivariate models with appropriate sampling weights.
The age standardized prevalence of urinary incontinence in the combined surveys was 51.1% in women and 13.9% in men. Prevalence in women increased from 49.5% in 2001 to 2002, to 53.4% in 2007 to 2008 (Ptrend=0.01) and in men from 11.5% to 15.1%, respectively (Ptrend=0.01). In women increased prevalence was partially explained by differences in age, race/ethnicity, obesity, diabetes and select chronic diseases across the survey periods. After adjustment the prevalence OR for 2007 to 2008 vs 2001 to 2002 decreased from 1.22 (95% CI 1.03-1.45) to 1.16 (95% CI 0.99-1.37). In men adjustment for potentially associated factors did not explain the increasing prevalence of urinary incontinence.
The age standardized prevalence of urinary incontinence increased in men and women from 2001 through 2008. Decreasing obesity and diabetes may lessen the burden of urinary incontinence, especially in women.
我们估计了美国成年人在 2001 年至 2008 年期间未经过其他潜在相关因素调整的尿失禁流行率趋势,以及调整后的趋势。
我们分析了参加 2001 年至 2008 年全国健康与营养调查周期的 17850 名 20 岁或以上成年人的数据。任何尿失禁均定义为在体力活动、到达厕所前和非体力活动期间对尿液泄漏问题的阳性反应。在此期间,与尿失禁相关的人口统计学和临床因素的变化包括年龄、种族/族裔、肥胖、糖尿病和慢性疾病(男性前列腺疾病)。使用适当的抽样权重调整后的多元模型确定标准化流行率估计值和尿失禁趋势的流行率比值比。
在综合调查中,女性尿失禁的标准化流行率为 51.1%,男性为 13.9%。女性的患病率从 2001 年至 2002 年的 49.5%增加到 2007 年至 2008 年的 53.4%(趋势 P=0.01),男性从 11.5%增加到 15.1%(趋势 P=0.01)。女性患病率的增加部分是由于在调查期间,年龄、种族/族裔、肥胖、糖尿病和某些慢性疾病的差异所致。调整后,2007 年至 2008 年与 2001 年至 2002 年相比,患病率比值比从 1.22(95%CI 1.03-1.45)下降到 1.16(95%CI 0.99-1.37)。在男性中,对潜在相关因素的调整并未解释尿失禁患病率的增加。
2001 年至 2008 年,男性和女性的尿失禁标准化流行率均有所增加。肥胖和糖尿病的减少可能会减轻尿失禁的负担,尤其是在女性中。