Rajpar Shanna, Guittat Lionel, Mergny Jean-Louis
Institut Gustave-Roussy, Villejuif, France.
Bull Cancer. 2011 Oct;98(9):999-1009. doi: 10.1684/bdc.2011.1378.
The 2009 Nobel Prize for Physiology and Medicine was awarded to Elizabeth H. Blackburn, Carol W. Greider and Jack K. Szostak for their work on telomeres and telomerase. This prize acknowledges their pionneering discoveries on chromosomal extremities. Telomeres are the nucleoproteic complexes that may be found at the ends of linear chromosomes. They are essential for genomic stability and are involved in aging and tumorogenesis.
2009年诺贝尔生理学或医学奖授予伊丽莎白·H·布莱克本、卡罗尔·W·格雷德和杰克·W·绍斯塔克，以表彰他们在端粒和端粒酶方面的研究成果。该奖项认可了他们在染色体末端方面的开创性发现。端粒是位于线性染色体末端的核蛋白复合体。它们对于基因组稳定性至关重要，并参与衰老和肿瘤发生过程。
