Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
Cell. 2009 Dec 11;139(6):1038-40. doi: 10.1016/j.cell.2009.11.033.
The 2009 Nobel Prize in Physiology or Medicine has been awarded to Elizabeth Blackburn, Carol Greider, and Jack Szostak for their contributions to our understanding of how the ends of eukaryotic chromosomes, telomeres, are replicated by a specialized reverse transcriptase, telomerase. I present a personal view of the telomere field, putting the contributions of these three Nobel laureates into historical context.
2009 年诺贝尔生理学或医学奖授予伊丽莎白·布莱克本、卡罗尔·格雷德以及杰克·绍斯塔克，以表彰他们对端粒如何通过一种特殊的逆转录酶——端粒酶来复制这一过程的理解所做出的贡献。我从个人角度介绍了端粒领域，将这三位诺贝尔奖得主的贡献置于历史背景中进行介绍。
