Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
FEBS J. 2013 Jul;280(14):3179. doi: 10.1111/febs.12357. Epub 2013 Jun 18.
The 2009 Nobel Prize in Physiology or Medicine was awarded to Drs Blackburn, Szostak and Greider for their discovery of how chromosomes are protected by telomeres and the enzyme telomerase. This minireview series consisting of three independent reviews discusses different aspects of this research, an area fuelling clinical applications in various human diseases including ageing and cancer.
2009 年诺贝尔生理学或医学奖授予布莱克本博士、绍斯塔克博士和格雷德博士,以表彰他们发现了染色体如何被端粒和端粒酶保护。这一系列由三篇独立综述组成的简评,讨论了这一研究的不同方面,该领域为包括衰老和癌症在内的各种人类疾病的临床应用提供了动力。