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简化的Free-Wilson方法应用于单纯疱疹病毒1型抗病毒7-氨基喹啉类药物。

Reduced Free-Wilson approach applied to HSV-1 antiviral 7-amino-quinolines.

作者信息

Mager P P

机构信息

Research Group for Pharmacochemistry, Faculty of Medicine, Karl Marx University, Leipzig.

出版信息

Pharmazie. 1990 May;45(5):359-60.

PMID:2168564
Abstract

The antiviral activity of a series of 7-aminoquinolines was determined against herpes simplex virus type 1 (HSV-1), and quantitative structure-activity relationships were studied by using the reduced Free-Wilson model. The predictive model power was tested.

摘要

测定了一系列7-氨基喹啉对1型单纯疱疹病毒（HSV-1）的抗病毒活性，并采用简化的Free-Wilson模型研究了定量构效关系。对预测模型的能力进行了测试。

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Pharmazie. 1990 May;45(5):359-60.
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