Pediatric Neurologist, The Hospital for Sick Children, Assistant Professor, Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON.
Epilepsy Curr. 2011 Mar;11(2):45-9. doi: 10.5698/1535-7511-11.2.45.
Sudden death is over 20 times more frequent in people with epilepsy than the general population. The literature on clinical risk factors is now able to define individuals at the highest risk. Despite these advances in our understanding of risk, the mechanism of sudden unexpected death in epilepsy remains elusive. While it is unlikely that a single mechanism will be found to explain all deaths, there have been recent advances that identify factors that play a critical role. This review provides an update on new advances in the understanding of sudden unexpected death in epilepsy.
癫痫患者的猝死率比普通人群高出 20 多倍。目前，有关临床危险因素的文献能够确定风险最高的个体。尽管我们对风险的认识有了这些进展，但癫痫猝死的机制仍然难以捉摸。虽然不太可能找到一个单一的机制来解释所有的死亡，但最近有一些进展确定了发挥关键作用的因素。这篇综述提供了对癫痫猝死理解的新进展的最新更新。
