特纳综合征中生长激素和促肾上腺皮质激素的分泌动态

Growth hormone and ACTH secretory dynamics in Turner's syndrome.

作者信息

Reschini E, D'Alberton A, Catania A, Motta T

机构信息

Service of Nuclear Medicine, Ospedale Maggiore di Milano, Italy.

出版信息

Gynecol Endocrinol. 1990 Jun;4(2):119-25. doi: 10.3109/09513599009012328.

DOI:10.3109/09513599009012328

PMID:2168659

Abstract

The secretory dynamics of GH and ACTH were studied in 14 patients with Turner's syndrome. The parameters investigated were plasma GH and cortisol responses to hypoglycemia, plasma cortisol circadian rhythm and suppressibility by dexamethasone, and response of urinary Porter-Silber chromogens to metyrapone. The results were mostly normal. These data do not support the hypothesis suggesting an abnormality of hypothalamic-pituitary function in Turner's syndrome.

摘要

对14例特纳综合征患者的生长激素（GH）和促肾上腺皮质激素（ACTH）分泌动力学进行了研究。所研究的参数包括血浆GH和皮质醇对低血糖的反应、血浆皮质醇昼夜节律以及地塞米松的抑制作用，还有尿波特-西尔伯色原对甲吡酮的反应。结果大多正常。这些数据不支持提示特纳综合征存在下丘脑-垂体功能异常的假说。