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与甲状腺功能减退相关的估计肾小球滤过率受损。这真的意味着急性肾衰竭吗？

Impaired estimated glomerular filtration rate associated with hypothyroidism. Does it really mean an acute renal failure?

作者信息

Brueckner Dieter, Brueckner Maike

机构信息

Practice, Maerkische Str. 237, Dortmund 44141, Germany.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.09.2008.0848. Epub 2009 Apr 3.

DOI:10.1136/bcr.09.2008.0848
PMID:21686601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3029058/
Abstract

A case of a young man with myopathy, elevated serum aminotransferase and serum creatinine levels is presented. He had a polymyositis-like-syndrome caused by hashimoto thyroiditis with hypothyroidism. Thyroid hormone replacement therapy led to improvement in both the clinical and laboratory abnormalities. With the established tests for estimating the glomerular filtration rate we cannot determine if there was really a reversible acute renal failure or not.

摘要

本文报告一例患有肌病、血清氨基转移酶和血清肌酐水平升高的年轻男性病例。他患有桥本甲状腺炎伴甲状腺功能减退所致的类多肌炎综合征。甲状腺激素替代疗法使临床和实验室异常情况均得到改善。利用现有的评估肾小球滤过率的检测方法，我们无法确定是否真的存在可逆性急性肾衰竭。

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Impaired estimated glomerular filtration rate associated with hypothyroidism. Does it really mean an acute renal failure?与甲状腺功能减退相关的估计肾小球滤过率受损。这真的意味着急性肾衰竭吗？
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.09.2008.0848. Epub 2009 Apr 3.
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本文引用的文献

1
Pediatric hypothyroidism presenting with a polymyositis-like syndrome and increased creatinine: report of three cases.表现为皮肌炎样综合征且肌酐升高的小儿甲状腺功能减退症：三例报告
J Pediatr Endocrinol Metab. 2008 Jan;21(1):89-92. doi: 10.1515/jpem.2008.21.1.89.
2
Influence of muscle mass and physical activity on serum and urinary creatinine and serum cystatin C.肌肉量和身体活动对血清及尿肌酐以及血清胱抑素C的影响
Clin J Am Soc Nephrol. 2008 Mar;3(2):348-54. doi: 10.2215/CJN.02870707. Epub 2008 Jan 30.
3
The influence of a cooked-meat meal on estimated glomerular filtration rate.一顿熟肉餐对估计肾小球滤过率的影响。
Ann Clin Biochem. 2007 Jan;44(Pt 1):35-42. doi: 10.1258/000456307779595995.
4
How to measure renal function in clinical practice.临床实践中如何测量肾功能。
BMJ. 2006 Oct 7;333(7571):733-7. doi: 10.1136/bmj.38975.390370.7C.
5
Onset of acquired autoimmune hypothyroidism in infancy: a presentation of delayed gross-motor development and rhabdomyolysis.
Eur J Pediatr. 2006 May;165(5):320-2. doi: 10.1007/s00431-005-0051-6. Epub 2006 Jan 21.
6
Cystatin C: unsuited to use as a marker of kidney function in the intensive care unit.胱抑素C：不适合用作重症监护病房肾功能的标志物。
Crit Care. 2005 Oct 5;9(5):531-2; author reply 531-2. doi: 10.1186/cc3541. Epub 2005 May 10.
7
Thyroid function differently affects serum cystatin C and creatinine concentrations.甲状腺功能对血清胱抑素C和肌酐浓度有不同影响。
J Endocrinol Invest. 2005 Apr;28(4):346-9. doi: 10.1007/BF03347201.
8
Rhabdomyolysis due to hypothyroidism.甲状腺功能减退所致横纹肌溶解症。
Nephrol Dial Transplant. 2005 Apr;20(4):847-8. doi: 10.1093/ndt/gfh745. Epub 2005 Feb 16.
9
Effects of creatine supplementation on the performance and body composition of competitive swimmers.补充肌酸对竞技游泳运动员成绩和身体成分的影响。
J Nutr Biochem. 2004 Aug;15(8):473-8. doi: 10.1016/j.jnutbio.2003.12.012.
10
Hypothyroid acute renal failure.甲状腺功能减退性急性肾衰竭
S D J Med. 2004 Mar;57(3):109-10.