Truffert Andre, Allali Gilles, Vokatch Natalia, Lalive Patrice H
University Hospital of Geneva, Micheli-du-Crest 24, Geneva 14, 1211, Switzerland.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.08.2008.0649. Epub 2009 Jan 23.
Neuromuscular complications of HIV are related to immunodeficiency, direct cytotoxicity of the virus or side effect of the treatments. Autoimmune disorders involving the nervous system, including Guillain-Barre syndrome, myositis and vasculitis, have been described in association with HIV. Neuromuscular junction autoimmune diseases such as myasthenia gravis have been occasionally reported in patients with HIV, whereas the Lambert-Eaton myasthenic syndrome (LEMS) has never been described. We report an unusual case of paucisymptomatic LEMS in a patient with HIV infection.
HIV的神经肌肉并发症与免疫缺陷、病毒的直接细胞毒性或治疗的副作用有关。涉及神经系统的自身免疫性疾病，包括格林-巴利综合征、肌炎和血管炎，已被描述与HIV相关。神经肌肉接头自身免疫性疾病，如重症肌无力，在HIV患者中偶尔有报道，而兰伯特-伊顿肌无力综合征（LEMS）从未被描述过。我们报告了一例HIV感染患者出现症状轻微的LEMS罕见病例。
