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面部创伤后三叉神经带状疱疹再激活伴顽固性疼痛:一例报告及文献复习

Reactivation of herpes zoster along the trigeminal nerve with intractable pain after facial trauma: a case report and literature review.

作者信息

Lin K-C, Wang Che-Chuan, Wang Kai-Yuan, Liao Yi-Chen, Kuo Jinn-Rung

机构信息

Chi-Mei Medical Center, Neurology, 901, Jong-Hwa Rd, Tainan, 710, Taiwan.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0525. Epub 2009 Apr 28.

Abstract

We report the rare occurrence of herpes zoster reactivation after facial trauma. Herpes zoster appeared in painful groups of distended vesicles containing clear fluid on an erythematous base within the secondary division of the trigeminal nerve. The patient was treated with acyclovir (intravenous, 250 mg, every 8 hours) combined with topical steroids and anti-neuropathic pain medication. The zoster-associated neuralgia subsided gradually 1.5 months after diagnosis. We illustrate this unique case to highlight the fact that reactivation of the varicella zoster virus from childhood chicken pox can reappear at a traumatic site in late adulthood.

摘要

我们报告了面部创伤后罕见的带状疱疹再激活病例。带状疱疹出现在三叉神经第二分支区域,表现为在红斑基础上成簇分布的疼痛性水疱,疱内含有清亮液体。患者接受了阿昔洛韦治疗(静脉注射,250毫克,每8小时一次),同时联合外用类固醇和抗神经性疼痛药物。带状疱疹相关性神经痛在诊断后1.5个月逐渐消退。我们展示这个独特病例以强调一个事实,即儿童期水痘感染的水痘-带状疱疹病毒再激活可在成年后期于创伤部位再次出现。

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