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[三叉神经带状疱疹:一例病例报告及文献复习]

[Herpes zoster of the trigeminal nerve: a case report and review of the literature].

作者信息

Carbone V, Leonardi A, Pavese M, Raviola E, Giordano M

机构信息

UOADU di Odontostomatologia, ASO S. Luigi Gonzaga, Orbassano, Turin.

出版信息

Minerva Stomatol. 2004 Jan-Feb;53(1-2):49-59.

Abstract

Herpes zoster (shingles) is caused when the varicella zoster virus that has remained latent since an earlier varicella infection (chicken-pox) is reactivated. Herpes Zoster is a less common and endemic disease than varicella: factors causing reactivation are still not well known, but it occurs in older and/or immunocompromised individuals. Following reactivation, centrifugal migration of herpes zoster virus (HZV) occurs along sensory nerves to produce a characteristic painful cutaneous or mucocutaneous vesicular eruption that is generally limited to the single affected dermatome. Herpes zoster may affect any sensory ganglia and its cutaneous nerve: the most common sites affected are thoracic dermatomes (56%), followed by cranial nerves (13%) and lumbar (13%), cervical (11%) and sacral nerves (4%). Among cranial nerves, the trigeminal and facial nerves are the most affected due to reactivation of HZV latent in gasserian and geniculated ganglia. The 1st division of the trigeminal nerve is commonly affected, whereas the 2nd and the 3rd are rarely involved. During the prodromal stage, the only presenting symptom may be odontalgia, which may prove to be a diagnostic challenge for the dentist, since many diseases can cause orofacial pain, and the diagnosis must be established before final treatment. A literature review of herpes zoster of the trigeminal nerve is presented and the clinical presentation, differential diagnosis and treatment modalities are underlined. A case report is presented.

摘要

带状疱疹是由水痘带状疱疹病毒引起的,该病毒自先前的水痘感染(水痘)后一直潜伏,现被重新激活。与水痘相比,带状疱疹是一种不太常见的地方性疾病:导致病毒重新激活的因素仍不明确,但它多发生于老年人和/或免疫功能低下的个体。病毒重新激活后,带状疱疹病毒(HZV)沿感觉神经离心性迁移,产生特征性的疼痛性皮肤或黏膜皮肤水疱疹,通常局限于单个受影响的皮节。带状疱疹可累及任何感觉神经节及其皮肤神经:最常受累的部位是胸段皮节(56%),其次是脑神经(13%)和腰段(13%)、颈段(11%)及骶段神经(4%)。在脑神经中,三叉神经和面神经受影响最为常见,这是由于半月神经节和膝状神经节中潜伏的HZV重新激活所致。三叉神经的第一支常受累,而第二支和第三支很少受累。在前驱期,唯一出现的症状可能是牙痛,这对牙医来说可能是一个诊断挑战,因为许多疾病都可引起口腔面部疼痛,且必须在最终治疗前确诊。本文对三叉神经带状疱疹进行了文献综述,并强调了其临床表现、鉴别诊断和治疗方式。同时还给出了一个病例报告。

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