伴有抗海马神经元膜抗体的可逆性边缘叶脑炎
Reversible limbic encephalitis with antibodies against the membranes of neurones of the hippocampus.
作者信息
Shimazaki Haruo, Ando Yoshihito, Nakano Imaharu, Dalmau Josep
机构信息
Department of Internal Medicine, Jichi Medical University, Tochigi, 329-0498, Japan.
出版信息
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0509. Epub 2009 Jan 23.
Abstract
The authors report a patient with limbic encephalitis associated with an ovarian teratoma. An antibody against the membranes of neurones of the hippocampus was identified in both serum and CSF. Immunosuppressive treatments such as plasmapheresis and high-dose intravenous immunoglobulin administration resulted in a rapid clinical recovery.
摘要
作者报告了一名患有与卵巢畸胎瘤相关的边缘叶脑炎的患者。在血清和脑脊液中均鉴定出一种针对海马神经元膜的抗体。诸如血浆置换和大剂量静脉注射免疫球蛋白等免疫抑制治疗导致了快速的临床康复。
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