Landthaler M, Braun-Falco O, Eckert F, Stolz W, Dorn M, Wolff H H
Department of Dermatology, Ludwig-Maximilians Universität Munich, West Germany.
Arch Dermatol. 1990 Sep;126(9):1203-7.
We encountered two patients with congenital multiple plaquelike glomus tumors. These lesions were present at birth and enlarged with body growth, attaining a diameter of up to 13 cm. The diagnosis was confirmed by histologic and electron-microscopic examination, which revealed the typical changes of glomus tumors. Immunocytochemistry findings demonstrated the tumor cells to be vimentin- and alpha-smooth muscle-actin-positive and desmin-negative. On ultrastructural examination, typical dense bodies and attachment plaques were easily found within the tumor cells. Glomus cells were coated by a thick basal lamina.
我们遇到了两名患有先天性多发性斑块状球瘤的患者。这些病变在出生时就存在，并随着身体生长而增大，直径可达13厘米。组织学和电子显微镜检查证实了诊断，显示出球瘤的典型变化。免疫细胞化学结果表明肿瘤细胞波形蛋白和α-平滑肌肌动蛋白呈阳性，结蛋白呈阴性。在超微结构检查中，肿瘤细胞内很容易发现典型的致密体和附着斑。球细胞被一层厚厚的基底膜包裹。
