Shukla Mridula, Mathews Anitha, Pandey Manoj
Institute of Medical Sciences, Pathology, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.03.2009.1721. Epub 2009 Jun 3.
A female patient presented with facial pain, discharge and headache. She had undergone excision of a palatal swelling 2 weeks previously, following which she had developed an oroantral fistula with necrosis of the palate. Imaging studies were suggestive of chronic sinusitis. A biopsy from the maxillary antrum revealed phaeohyphomycosis, a group of fungal infections caused by saprophytic fungi. The patient was treated with antifungal treatment and had a complete response. Phaeohyphomycosis is of rare occurrence in the paranasal sinus and in patients who are immunocompetant. There are only eight previous reports of this occurrence in the literature worldwide.
一名女性患者出现面部疼痛、分泌物增多及头痛症状。她在两周前接受了腭部肿物切除术,术后出现了腭部坏死的口腔上颌窦瘘。影像学检查提示慢性鼻窦炎。上颌窦活检显示为暗色丝孢霉病,这是一组由腐生真菌引起的真菌感染。该患者接受了抗真菌治疗并完全康复。暗色丝孢霉病在鼻窦及免疫功能正常的患者中较为罕见。此前全球文献中仅有八例相关报道。