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面部皮下外瓶霉病表现为鼻孢子菌病。

Subcutaneous phaeohyphomycosis of the face presenting as rhinoentomophthoramycosis.

机构信息

Department of Dermatology, Dr. Rajendra Prasad Government Medical College, Kangra (Tanda), Himachal Pradesh, India.

出版信息

Int J Dermatol. 2013 Sep;52(9):1105-8. doi: 10.1111/ijd.12166. Epub 2013 Jul 8.

Abstract

OBJECTIVES

Subcutaneous phaeohyphomycosis is the most common variety of phaeohyphomycosis and presents as asymptomatic or mildly painful, localized cysts, abscesses, or sometimes chromoblastomycosis-like lesions over the feet, legs, or hands in about 60-85% of cases. It usually afflicts adults with some degree of immunosuppression.

METHODS

We report a 30-year-old man, who presented with features of recurrent sinusitis (episodes of fever, nasal stuffiness, paranasal sinus pain, and tenderness), mucosal hypertrophy of the maxillary sinuses, and mid-face swelling that was freely mobile and suggestive of rhinoentomophthoramycosis. He had no other associated illness.

RESULTS

Histology suggested tumid lupus erythematosus. The diagnosis was based on Fonsecaea pedrosoi cultured from a biopsy specimen.

CONCLUSIONS

Combination therapy with itraconazole and saturated solution of potassium iodide (SSKI) was more effective than itraconazole used alone.

摘要

目的

皮下外瓶霉病是外瓶霉病中最常见的一种,约 60-85%的病例表现为无症状或轻度疼痛的局限性囊肿、脓肿,或有时在足部、腿部或手部出现类似于着色芽生菌病的病变。它通常影响有一定程度免疫抑制的成年人。

方法

我们报告了一名 30 岁男性,他表现为复发性鼻窦炎(发热、鼻塞、鼻窦疼痛和压痛发作)、上颌窦黏膜肥大以及中面部肿胀,这些症状具有活动性和提示 rhinoentomophthoramycosis 的特征。他没有其他相关疾病。

结果

组织学提示肿胀性红斑狼疮。诊断基于从活检标本中培养出的佩德罗索外瓶霉。

结论

伊曲康唑和碘化钾饱和溶液(SSKI)联合治疗比单独使用伊曲康唑更有效。

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