Department of Dermatology, Dr. Rajendra Prasad Government Medical College, Kangra (Tanda), Himachal Pradesh, India.
Int J Dermatol. 2013 Sep;52(9):1105-8. doi: 10.1111/ijd.12166. Epub 2013 Jul 8.
Subcutaneous phaeohyphomycosis is the most common variety of phaeohyphomycosis and presents as asymptomatic or mildly painful, localized cysts, abscesses, or sometimes chromoblastomycosis-like lesions over the feet, legs, or hands in about 60-85% of cases. It usually afflicts adults with some degree of immunosuppression.
We report a 30-year-old man, who presented with features of recurrent sinusitis (episodes of fever, nasal stuffiness, paranasal sinus pain, and tenderness), mucosal hypertrophy of the maxillary sinuses, and mid-face swelling that was freely mobile and suggestive of rhinoentomophthoramycosis. He had no other associated illness.
Histology suggested tumid lupus erythematosus. The diagnosis was based on Fonsecaea pedrosoi cultured from a biopsy specimen.
Combination therapy with itraconazole and saturated solution of potassium iodide (SSKI) was more effective than itraconazole used alone.
皮下外瓶霉病是外瓶霉病中最常见的一种,约 60-85%的病例表现为无症状或轻度疼痛的局限性囊肿、脓肿,或有时在足部、腿部或手部出现类似于着色芽生菌病的病变。它通常影响有一定程度免疫抑制的成年人。
我们报告了一名 30 岁男性,他表现为复发性鼻窦炎(发热、鼻塞、鼻窦疼痛和压痛发作)、上颌窦黏膜肥大以及中面部肿胀,这些症状具有活动性和提示 rhinoentomophthoramycosis 的特征。他没有其他相关疾病。
组织学提示肿胀性红斑狼疮。诊断基于从活检标本中培养出的佩德罗索外瓶霉。
伊曲康唑和碘化钾饱和溶液(SSKI)联合治疗比单独使用伊曲康唑更有效。