Qureshi Asim, Kayani Naila, Gulzar Rubina
Pathology, Aga Khan University, Stadium Road, Karachi, Pakistan, Karachi, 74800, Pakistan.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.01.2009.1442. Epub 2009 Jun 18.
Adenomyoepitheliomas are uncommon breast tumours. By definition they have a prominent component of myoepithelial cells, in addition to glandular elements lined by epithelial cells. Malignant adenomyoepithelioma of the breast is even more rare, characterised by malignant proliferation of epithelial and myoepithelial cells that show characteristic histological and immunohistochemical features. Only 11 cases have been reported to date. A case of malignant adenomyoepithelioma of the breast is reported.
腺肌上皮瘤是一种罕见的乳腺肿瘤。根据定义,除了由上皮细胞衬里的腺性成分外,它们还含有显著的肌上皮细胞成分。乳腺恶性腺肌上皮瘤更为罕见,其特征是上皮细胞和肌上皮细胞的恶性增殖,并表现出特征性的组织学和免疫组化特征。迄今为止,仅报道过11例。本文报道了1例乳腺恶性腺肌上皮瘤。