Lari Eisa A, Lari Ali A, Alsaeed Talal
General Surgery Department, Jaber Al-Ahmad Hospital, Ministry of Health, Kuwait.
Int J Surg Case Rep. 2020;72:56-58. doi: 10.1016/j.ijscr.2020.05.061. Epub 2020 May 30.
Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation.
Here we present a case of a young, previously healthy female who initially presented with a painless breast lump. The patient underwent wide local excision for atypical cells with squamous metaplasia by core biopsy, but final histopathology showed AME with carcinoma. Thus, a mastectomy and a sentinel lymph node biopsy was undertaken. The patient had an uneventful recovery and no recurrence after the second surgery.
Malignant transformation of adenomyoepithelioma is reported in a small number of cases. Benign AME may be treated with wide local excision as recurrence is rare locally. Whereas malignant AME tends to be treated with simple mastectomy with or without lymph node biopsy.
乳腺恶性腺肌上皮瘤（AME）是一种罕见的乳腺癌亚型。AME大多为良性疾病，很少发生恶性转化。
我们在此报告一例年轻的既往健康女性，最初表现为无痛性乳腺肿块。患者因经粗针活检发现具有鳞状化生的非典型细胞而接受了广泛局部切除，但最终组织病理学显示为伴有癌的AME。因此，进行了乳房切除术和前哨淋巴结活检。患者恢复顺利，二次手术后未复发。
少数病例报告了腺肌上皮瘤的恶性转化。良性AME可通过广泛局部切除进行治疗，因为局部复发很少见。而恶性AME倾向于采用单纯乳房切除术，可伴有或不伴有淋巴结活检。
