Itani Mohamad Hassan, Fakih Hadi
American University Hospital of Beirut, Pediatrics, Cairo Street, Beirut, 113-6044/29D, Lebanon.
BMJ Case Rep. 2009;2009:bcr0120091476. doi: 10.1136/bcr.01.2009.1476. Epub 2009 May 12.
Haemangioma is the most common vascular tumour of childhood. Most cases require no therapeutic intervention, with spontaneous involution by 5-9 years of age. Some haemangiomas may become large in size impinging on vital structures such as eyes, mouth, nose or larynx, and require certain therapeutic interventions to prevent major morbidities. The usual treatments include oral/intralesional steroids, α interferon, cytotoxins, remobilisation, pulsed dye laser and cosmetic surgery resection; these treatments are not free of multiple complications and toxic side effects. This report describes the case of a 4-month-old female baby with progressively increasing haemangioma of the right upper eyelid impinging over the upper outer visual field. The haemangioma responded promptly to low-dose oral propranolol. A clinical response was noticed few days after the start of the treatment and was free of any major side effects.
血管瘤是儿童期最常见的血管肿瘤。大多数病例无需治疗干预,5至9岁时可自行消退。一些血管瘤可能会长得很大,压迫眼睛、嘴巴、鼻子或喉部等重要结构,需要进行某些治疗干预以预防严重并发症。常用的治疗方法包括口服/瘤内注射类固醇、α干扰素、细胞毒素、重新活动、脉冲染料激光和美容手术切除;这些治疗并非没有多种并发症和毒副作用。本报告描述了一名4个月大的女婴,右上眼睑的血管瘤逐渐增大,影响到上外侧视野。该血管瘤对低剂量口服普萘洛尔反应迅速。治疗开始几天后就观察到了临床反应,且没有任何严重副作用。