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Semiquinone radicals of methylamine dehydrogenase, methoxatin, and related o-quinones: a pulse radiolysis study.

作者信息

McWhirter R B, Klapper M H

机构信息

Department of Chemistry, Ohio State University, Columbus 43210.

出版信息

Biochemistry. 1990 Jul 24;29(29):6919-26. doi: 10.1021/bi00481a023.

Abstract

Methoxatin is a novel o-quinone coenzyme found in a variety of dehydrogenases and oxidases. In this paper we present the visible absorption spectra, apparent pKa, and midpoint potentials of the methoxatin and two analogous phenanthrolinedione semiquinones. We have also obtained absorption spectra for the semiquinone forms of the methoxatin-containing holoenzyme methylamine dehydrogenase and of its resolved methoxatin-containing subunit. The two protein and the methoxatin semiquinone spectra all differ from one another.

摘要

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