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表面增强激光解吸电离飞行时间质谱技术在癌症临床诊断中的应用。

The application of SELDI-TOF-MS in clinical diagnosis of cancers.

作者信息

Liu Chibo

机构信息

Department of Laboratory Medicine, The Affiliated Taizhou Municipal Hospital, Taizhou Medical College, Taizhou, Zhejiang Province, China.

出版信息

J Biomed Biotechnol. 2011;2011:245821. doi: 10.1155/2011/245821. Epub 2011 May 23.

DOI:10.1155/2011/245821
PMID:21687541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3114543/
Abstract

Cancer diagnosis is important, and the early diagnosis of cancers could predict a more successful treatment. The proteomic studies emerged to be useful in combined analyses of samples from patients and provide more accurate diagnosis when compared to the single-factor-based diagnosis. In recent years, cancer detection with surface-enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF MS) is flourishing and brought significant progress in this area. This paper summarizes some recent results with this technique for cancer diagnosis.

摘要

癌症诊断至关重要，癌症的早期诊断能够预示更成功的治疗效果。蛋白质组学研究在对患者样本进行综合分析时显示出其有用性，并且与基于单一因素的诊断相比，能提供更准确的诊断。近年来，利用表面增强激光解吸/电离飞行时间质谱（SELDI-TOF MS）进行癌症检测的技术蓬勃发展，并在该领域取得了显著进展。本文总结了该技术在癌症诊断方面的一些最新成果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df37/3114543/f29f879c840f/JBB2011-245821.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df37/3114543/cbfae08f1ddb/JBB2011-245821.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df37/3114543/89f3d8a08112/JBB2011-245821.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df37/3114543/f29f879c840f/JBB2011-245821.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df37/3114543/cbfae08f1ddb/JBB2011-245821.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df37/3114543/89f3d8a08112/JBB2011-245821.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df37/3114543/f29f879c840f/JBB2011-245821.003.jpg

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