Lampe Frank, Sufi-Siavach Anusch, Bohlen Karina E, Hille Ekkehard, Dries Sebastian P M
Schön Klinik Hamburg-Eilbek, Dehnhaide 120, DE 22081 Hamburg, Germany.
Open Orthop J. 2011;5:201-8. doi: 10.2174/1874325001105010201. Epub 2011 May 27.
The mobile bearing designs have not yet been shown to improve clinical outcome of total knee arthroplasty (TKA). In this prospective randomized study, we compared the short-term clinical results of a mobile bearing implant with those of the fixed bearing version of the same implant.
We randomized 100 knees into two double-blind groups who received either the fixed (FB, 52 knees) or the mobile bearing (MB, 48 knees) version of the same implant. We used navigation to standardize the surgical technique. For up to one year, we recorded the Knee Society (KSS) and Oxford (OXF) scores. We performed an exploratory analysis of variance (ANOVA) to determine the influence of baseline scores as covariate and the extent of improvement in clinical outcome over time.
After one year, we did not detect any statistically significant difference between the two groups. The KSS scores differed by 2 points, the OXF scores by 1.1 points.
Even with identical geometry of implant surfaces and a navigated surgical technique, first-year results do not support a preference for either a fixed or a mobile design.
活动轴承设计尚未被证明能改善全膝关节置换术（TKA）的临床效果。在这项前瞻性随机研究中，我们比较了活动轴承植入物与同一植入物的固定轴承版本的短期临床结果。
我们将100个膝关节随机分为两个双盲组，分别接受同一植入物的固定（FB，52个膝关节）或活动轴承（MB，48个膝关节）版本。我们使用导航来规范手术技术。长达一年的时间里，我们记录了膝关节协会（KSS）和牛津（OXF）评分。我们进行了探索性方差分析（ANOVA），以确定基线评分作为协变量的影响以及临床结果随时间的改善程度。
一年后，我们未发现两组之间有任何统计学上的显著差异。KSS评分相差2分，OXF评分相差1.1分。
即使植入物表面几何形状相同且采用导航手术技术，第一年的结果也不支持对固定或活动设计有偏好。
