Rosenbaum Robert, Trousdale James, Josić Krešimir
Department of Mathematics, University of Houston Houston, TX, USA.
Front Neurosci. 2011 Apr 28;5:58. doi: 10.3389/fnins.2011.00058. eCollection 2011.
Neurons integrate inputs from thousands of afferents. Similarly, some experimental techniques record the pooled activity of large populations of cells. When cells in these populations are correlated, the correlation coefficient between the collective activity of two subpopulations is typically much larger than the correlation coefficient between individual cells: The act of pooling individual cell signals amplifies correlations. We give an overview of this phenomenon and present several implications. In particular, we show that pooling leads to synchronization in feedforward networks and that it can amplify and otherwise distort correlations between recorded signals.
神经元整合来自数千个传入神经的输入。同样，一些实验技术记录大量细胞的汇总活动。当这些群体中的细胞相互关联时，两个亚群的集体活动之间的相关系数通常远大于单个细胞之间的相关系数：汇总单个细胞信号的行为会放大相关性。我们概述了这一现象并提出了一些影响。特别是，我们表明汇总会导致前馈网络中的同步，并且它可以放大并以其他方式扭曲记录信号之间的相关性。
