Department of Physiology, St Mark's Hospital, Harrow, London, UK.
Colorectal Dis. 2012 Feb;14(2):200-4. doi: 10.1111/j.1463-1318.2011.02568.x.
Increasing life expectancy will increase the number of elderly patients with faecal incontinence. The study aimed to assess the safety and efficacy of sacral nerve stimulation (SNS) in patients over the age of 65 years.
Patients aged over 65 years, who underwent temporary SNS from 1996 for faecal incontinence unresponsive to conservative treatment, were followed prospectively.
Between January 1996 and December 2009, 30 patients [mean age 69.3 years (SD, 3.4)] underwent temporary SNS. Twenty-three (77%) had a >50% improvement in the St Mark's Continence Score and progressed to permanent SNS implantation. Their mean (±SD) score increased from 19 (3.2) at baseline to 8 (3.4) during temporary SNS and to 9 (3.4) 3 months after permanent SNS and 10 (3.7) at the latest median follow up (IQR) of 44 (20-150) months. The corresponding values at the same intervals for urgency [mean (±SD) min] were 1 (1.4), 8 (5.2), 8 (5) and 8 (5.4) and for incontinence episodes per 2 weeks [median (±IQR)] were 10 (7-14), 1 (0-5), 2 (0-5) and 0 (0-6).
SNS is an effective treatment for faecal incontinence in patients over 65 years.
预期寿命的延长将增加患有粪便失禁的老年患者数量。本研究旨在评估骶神经刺激（SNS）在 65 岁以上患者中的安全性和疗效。
对 1996 年以来因保守治疗无效而接受临时 SNS 治疗的 65 岁以上粪便失禁患者进行前瞻性随访。
1996 年 1 月至 2009 年 12 月期间，30 例患者（平均年龄 69.3 岁，标准差 3.4）接受了临时 SNS。23 例（77%）的 St Mark 失禁评分改善>50%，并进展为永久性 SNS 植入。他们的平均（±标准差）评分从基线时的 19（3.2）增加到临时 SNS 时的 8（3.4），再增加到永久性 SNS 后 3 个月时的 9（3.4）和最近的中位数随访时的 10（3.7）（IQR 44（20-150）个月）。同一时间间隔内尿急的平均（±标准差）分钟数分别为 1（1.4）、8（5.2）、8（5）和 8（5.4），每 2 周失禁发作次数的中位数（IQR）分别为 10（7-14）、1（0-5）、2（0-5）和 0（0-6）。
SNS 是 65 岁以上患者粪便失禁的有效治疗方法。
