Physiology Unit, St Mark's Hospital, Middlesex, UK.
Colorectal Dis. 2011 Sep;13(9):1030-4. doi: 10.1111/j.1463-1318.2010.02383.x.
Sacral nerve stimulation (SNS) is considered a first-line surgical treatment option for faecal incontinence. There is little information on long-term results. The results of SNS for faecal incontinence performed at a single centre over a 10-year period are reported.
A cohort analysis of consecutive patients treated with SNS for faecal incontinence over a 10-year period was carried out. Data were collected prospectively using bowel habit diaries and St Mark's and Cleveland Clinic incontinence scores. Treatment success was defined as a >50% reduction in episodes of faecal incontinence compared with baseline.
Temporary SNS was performed in 118 patients, and 91 (77%) were considered suitable for chronic stimulation. The median period of follow up was 22 (1-138) months. Seventy patients were followed for 1 year with success in 63 (90%). Of 18 patients followed for 5 years, 15 (83%) reported continued success, 11 (61%) maintained full efficacy, 4 (22%) reported some loss, and 3 (17%) reported complete loss. Three patients with a 10-year follow up had no loss in efficacy. Overall, complete loss of efficacy was observed in 14 (16%) patients at a median of 11.5 months following implantation. A further 5 (6%) patients showed deterioration with time. In 9 (47%), no reason for the deterioration in symptoms could be identified.
SNS can be effective for up to 10 years. Some patients experience deterioration in symptoms over time. The reasons for this are often not evident.
骶神经刺激（SNS）被认为是治疗粪便失禁的一线手术治疗选择。关于长期结果的信息很少。报告了在单个中心进行的 SNS 治疗粪便失禁 10 年期间的结果。
对 10 年内接受 SNS 治疗粪便失禁的连续患者进行了队列分析。使用排便习惯日记和圣马克和克利夫兰诊所失禁评分前瞻性地收集数据。治疗成功定义为与基线相比，粪便失禁发作减少>50%。
在 118 例患者中进行了临时 SNS，其中 91 例（77%）被认为适合慢性刺激。中位随访时间为 22 个月（1-138 个月）。70 例患者随访 1 年，63 例（90%）成功。18 例随访 5 年的患者中，15 例（83%）报告持续成功，11 例（61%）保持完全疗效，4 例（22%）报告部分丧失，3 例（17%）报告完全丧失。3 例随访 10 年的患者无疗效丧失。总体而言，植入后中位时间为 11.5 个月，14 例（16%）患者完全丧失疗效。另有 5 例（6%）患者随时间恶化。在 9 例（47%）中，无法确定症状恶化的原因。
SNS 最长可有效 10 年。一些患者随时间推移出现症状恶化。其原因往往不明显。
