Division of Gastroenterology and Hepatology, William J. von Liebig Transplant Center, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Clin Liver Dis. 2011 May;15(2):385-93, vii-x. doi: 10.1016/j.cld.2011.03.005.
Despite significant advances in nonsurgical treatments of hepatocellular carcinoma, these approaches rarely result in cure. Surgery remains the mainstay of curative therapy for hepatocellular carcinoma. Liver transplantation, in particular, has emerged as one of the most beneficial therapeutic modalities. Questions remain, however, regarding hepatocellular carcinoma surveillance, the choice of surgical resection versus transplantation, the role of chemotherapy, optimal selection criteria for transplantation, and the role of ablative therapies to halt tumor progression and downsize tumors exceeding transplant criteria.
尽管在肝细胞癌的非手术治疗方面取得了重大进展，但这些方法很少能治愈疾病。手术仍然是治疗肝细胞癌的主要方法。肝移植，特别是，已成为最有益的治疗方式之一。然而，关于肝细胞癌的监测、手术切除与移植的选择、化疗的作用、移植的最佳选择标准以及消融疗法在阻止肿瘤进展和缩小超出移植标准的肿瘤方面的作用等问题仍有待探讨。
